Contribution of the Solvent Extraction Method for Phenolic Compounds, Flavonoids, and Fucoxanthin to the Antioxidative Properties in Extracts of Chaetoceros tenuissimus Meunier

Chaetoceros sp. has been found to possess significant amounts of valuable fucoxanthin, phenolics, and flavonoids, with enormous nutraceutical antioxidant potential. The aim this study was employ ultrasound-assisted extraction determine the properties extracts prepared from tenuissimus using different solvents: Propylene glycol (PG), acetone (AC), methanol (ME), difference ultrasonication times (15 30 min). total phenolic (TPC), flavonoid (TFC), fucoxanthin (FUC) contents were evaluated. Antioxidant capacity evaluated by DPPH ABTS radical-scavenging assays lipid peroxidation TBARS. FUC content analyzed HPLC-DAD. 30-min PG extract (PG-30) exhibited highest TPC (2.75 ± 0.14 mg GAE.g−1 DW), (8.76 0.06 FUC. g−1). Concerning capacity, PG-30 most effective against DPPH• (IC50 = 970.19 7.70 µg. mL−1) TBARS 717.05 1.45 mL−1), while 15-min (PG-15) presented inhibitory activity ABTS+• 150.02 6.95 mL−1). findings demonstrate that C. exhibit high potential activity, likely associated their could be used in cosmetic preparations as phytonutrients. HIGHLIGHTS Meunier Chonburi province, Thailand High activities ultrasound assisted solvents correlation between chemical substances GRAPHICAL ABSTRACT